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產(chǎn)品名稱：BIX02189
產(chǎn)品型號(hào)：
產(chǎn)品廠商：TargetMol
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BIX02189

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Product details
Product details
Purpose	BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM, also inhibits ERK5 catalytic activity with IC50 of 59 nM in cell-free assays, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.
Characteristics	Target: MEK inhibitor Receptor: MEK5/ERK5/TGFβ/MEK1/ERK1/JNK1/EGFR/STK16
Purification	All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity	97?% +
Formula	C27H28N4O2
Solubility	100 mM in DMSO

Target details
Target details
Molecular Weight	440.54 g/mol
CAS-No	1094614-85-3

Application Details
Application Details
Application Notes	Optimal working dilution should be determined by the investigator.
Restrictions	For Research Use only

Handling
Handling
Format	Solid
Storage	-20 °C
Storage Comment	For the majority of compounds, they could be dissolved in DMSO or other organic solvent. Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience. Several freeze/thaw cycles should not damage the activity of our small molecule products. However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date	24 months